Selected article for: "chikungunya virus and encephalitis virus"
Author: Lundstrom, Kenneth
Title: Alphavirus-Based Vaccines
  • Document date: 2014_6_16
    • ID: 07iwwsfz_1
    Snippet: Alphaviruses are single-stranded RNA viruses with an envelope structure belonging to the family of Togaviridae [1] . Certain alphaviruses have been associated with pathogenicity, resulting in global fever epidemics, such as observed recently for Chikungunya virus [2] . Furthermore, Semliki Forest virus (SFV) [3] and Venezuelan equine encephalitis (VEE) virus [4] have been identified as the causes of an outbreak of febrile illness in Central Afric.....
    Document: Alphaviruses are single-stranded RNA viruses with an envelope structure belonging to the family of Togaviridae [1] . Certain alphaviruses have been associated with pathogenicity, resulting in global fever epidemics, such as observed recently for Chikungunya virus [2] . Furthermore, Semliki Forest virus (SFV) [3] and Venezuelan equine encephalitis (VEE) virus [4] have been identified as the causes of an outbreak of febrile illness in Central Africa and an epidemic in horses and humans in South America, respectively. Despite this potential concern, several alphaviruses, including SFV [5] , Sindbis virus (SIN) [6] and VEE [7] have been subjected to the engineering of vectors for heterologous gene expression. In these cases, attenuated strains have been employed.

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