Author: Saeed, Abdullah F. U. H.; Wang, Rongzhi; Ling, Sumei; Wang, Shihua
Title: Antibody Engineering for Pursuing a Healthier Future Document date: 2017_3_28
ID: 0fegsm1v_89
Snippet: The study of epitopes and mimotopes in the interactions of antigen-antibody binding was the earliest application of PDT . Mimotopes are miniscule peptides that mimic linear, intermittent, or non-peptide epitopes. It was noted that scFv, Fab fragment, and VHH domains could be displayed on the phage successfully (Tonelli et al., 2012) . This laid the foundation of new molecular recognition techniques to determine protein folding, stability, structu.....
Document: The study of epitopes and mimotopes in the interactions of antigen-antibody binding was the earliest application of PDT . Mimotopes are miniscule peptides that mimic linear, intermittent, or non-peptide epitopes. It was noted that scFv, Fab fragment, and VHH domains could be displayed on the phage successfully (Tonelli et al., 2012) . This laid the foundation of new molecular recognition techniques to determine protein folding, stability, structure-to-function relationships, and other related protein-protein interactions. The fusion of many ligands with phage particles has enrich phage displayed cDNA libraries significantly (Vithayathil et al., 2011) .
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