Author: Saeed, Abdullah F. U. H.; Wang, Rongzhi; Ling, Sumei; Wang, Shihua
Title: Antibody Engineering for Pursuing a Healthier Future Document date: 2017_3_28
ID: 0fegsm1v_106
Snippet: Immunomodulatory techniques are persistently progressing to expand the clinical efficacy of therapeutic antibodies. Cell surface antigens exhibit a wide array of targets that are overexpressed, mutated or selectively expressed, and selected for modulated antibody-based therapeutics. The technology functions through engineering alterations in antigen or receptor function, the immune system i.e., altering Fc function and T cell activation and antib.....
Document: Immunomodulatory techniques are persistently progressing to expand the clinical efficacy of therapeutic antibodies. Cell surface antigens exhibit a wide array of targets that are overexpressed, mutated or selectively expressed, and selected for modulated antibody-based therapeutics. The technology functions through engineering alterations in antigen or receptor function, the immune system i.e., altering Fc function and T cell activation and antibody conjugated drug delivery system (DDS) targeting a specific antigen. Immunomodulatory antibodies have gained significant clinical success (Scott et al., 2012) .
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