Author: Saeed, Abdullah F. U. H.; Wang, Rongzhi; Ling, Sumei; Wang, Shihua
Title: Antibody Engineering for Pursuing a Healthier Future Document date: 2017_3_28
ID: 0fegsm1v_125
Snippet: The detection of antibodies against infectious agents and the construction of rapid and sensitive antibody-based immunodiagnostic test kits is an important part of basic and clinical research. Assays have been developed against pathogens, toxins, and infectious proteins/peptides (Ahmad et al., 2012) . The production of antibodies depends on specific protein titers, extent of immunity, and identification of B cell responses (Burbelo et al., 2010) .....
Document: The detection of antibodies against infectious agents and the construction of rapid and sensitive antibody-based immunodiagnostic test kits is an important part of basic and clinical research. Assays have been developed against pathogens, toxins, and infectious proteins/peptides (Ahmad et al., 2012) . The production of antibodies depends on specific protein titers, extent of immunity, and identification of B cell responses (Burbelo et al., 2010) . Antibodies are routinely detected by ELISA and other immunoassays. Accessibility of full length DNA sequences is useful for the rapid and robust systematic identification of antigens by recombinant proteins using protein arrays for complete proteome analysis (Kierny et al., 2012) . Furthermore, numerous novel high-throughput dominant immunoassays are used to detect antibody responses against antigens (Burbelo et al., 2010) .
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