Author: Miguel, Maria Graça
Title: Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review Document date: 2010_12_15
ID: 1dfzj1b3_133
Snippet: Early growth response factor-1 (Erg-1) is a transcription factor that plays a regulatory role in the expression of many important genes of inflammation (cytokine, cell adhesion molecules, and immunoreceptors). The human monocyte cell line THP-1 is often used as a model for tissue macrophages. Zhou et al. (2007) [149] showed that 1,8-cineole inhibited the Egr-1 synthesis and nuclear localization induced by LPS in THP-1 cells but did not affect the.....
Document: Early growth response factor-1 (Erg-1) is a transcription factor that plays a regulatory role in the expression of many important genes of inflammation (cytokine, cell adhesion molecules, and immunoreceptors). The human monocyte cell line THP-1 is often used as a model for tissue macrophages. Zhou et al. (2007) [149] showed that 1,8-cineole inhibited the Egr-1 synthesis and nuclear localization induced by LPS in THP-1 cells but did not affect the LPS-induced NF-κB expression in nuclei. Therefore, the authors concluded that 1,8-cineole may preferentially block the effect of Egr-1 by inhibiting the synthesis of Egr-1 and preventing Egr-1 nuclear internalization instead of NF-κB inhibition [149] . Some authors reported that α-pinene clearly inhibited the translocation of NF-κB/p65 protein into nuclei in LPS-stimulated THP-1 cells, through the increase of expression of IκBα protein [150, 151] .
Search related documents:
Co phrase search for related documents- cell adhesion and human monocyte: 1, 2
- cell adhesion and human monocyte cell line: 1
- cell adhesion and important gene: 1, 2
- cell adhesion and LPS induce: 1
- cell adhesion and NF κB expression: 1, 2, 3
- cell adhesion molecule and LPS induce: 1
- cell adhesion molecule and NF κB expression: 1
- cell line and growth response: 1, 2, 3, 4
- cell line and human monocyte: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
- cell line and human monocyte cell line: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- cell line and important gene: 1, 2, 3, 4, 5, 6
- cell line and LPS induce: 1, 2, 3
- cell line and NF κB expression: 1, 2, 3, 4, 5
- cell LPS induce and human monocyte: 1
- cell LPS induce and human monocyte cell line: 1
- cell LPS induce and LPS induce: 1, 2, 3, 4
- cell LPS induce and NF κB expression: 1
- early growth response and growth response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23
- growth response and important gene: 1
Co phrase search for related documents, hyperlinks ordered by date