Author: Gwon, Yong-Dae; Strand, Mårten; Lindqvist, Richard; Nilsson, Emma; Saleeb, Michael; Elofsson, Mikael; Överby, Anna K.; Evander, Magnus
Title: Antiviral Activity of Benzavir-2 against Emerging Flaviviruses Document date: 2020_3_22
ID: 0ym40eki_58
Snippet: To further assess the inhibition of plaque formation by benzavir-2, we quantified the production of the infectious progeny virus. Benzavir-2 strongly inhibited the production of the progeny ZIKV virus particles released to the cellular surroundings. From a drug development and physiological perspective, a pronounced inhibition of the progeny virus production is favorable, because the ultimate aim of an antiviral drug is to diminish the viral spre.....
Document: To further assess the inhibition of plaque formation by benzavir-2, we quantified the production of the infectious progeny virus. Benzavir-2 strongly inhibited the production of the progeny ZIKV virus particles released to the cellular surroundings. From a drug development and physiological perspective, a pronounced inhibition of the progeny virus production is favorable, because the ultimate aim of an antiviral drug is to diminish the viral spread.
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