Author: Perdomo, German; Dong, H. Henry
Title: Apolipoprotein D in Lipid Metabolism and Its Functional Implication in Atherosclerosis and Aging Document date: 2008_12_12
ID: 167z915s_7
Snippet: Niemann-Pick Type C (NPC) disease is a human neurodegenerative disorder characterized by impaired intracellular cholesterol transport [25] . Interestingly, in rodent models of the human NPC disease, apoD protein levels are markedly elevated by 30-fold in the brain and 6-fold in plasma, correlating with increased intracellular cholesterol storage [26, 27] . These findings implicate apoD in the pathogenesis of NPC disease......
Document: Niemann-Pick Type C (NPC) disease is a human neurodegenerative disorder characterized by impaired intracellular cholesterol transport [25] . Interestingly, in rodent models of the human NPC disease, apoD protein levels are markedly elevated by 30-fold in the brain and 6-fold in plasma, correlating with increased intracellular cholesterol storage [26, 27] . These findings implicate apoD in the pathogenesis of NPC disease.
Search related documents:
Co phrase search for related documents- cholesterol storage and NPC disease: 1, 2
- cholesterol transport and NPC disease: 1, 2, 3, 4, 5
- neurodegenerative disorder and NPC disease: 1
Co phrase search for related documents, hyperlinks ordered by date