Selected article for: "κB nuclear factor and nuclear factor"
Author: Miguel, Maria Graça
Title: Antioxidant and Anti-Inflammatory Activities of Essential Oils: A Short Review
  • Document date: 2010_12_15
    • ID: 1dfzj1b3_113
    Snippet: There are three isoforms of NOS: constitutive (cNOS), endothelial (eNOS) and the other is cytokine-inducible NOS (iNOS). Inflammatory mediators such as IL-1, TNF-α or LPS stimulate iNOS expression in rodent macrophages in vitro. NO production and/or iNOS expression are also induced by inflammatory mediators in a wide variety of mammalian cells, producing large amounts of NO for prolonged time periods [25] . iNOS catalises the production of large.....
    Document: There are three isoforms of NOS: constitutive (cNOS), endothelial (eNOS) and the other is cytokine-inducible NOS (iNOS). Inflammatory mediators such as IL-1, TNF-α or LPS stimulate iNOS expression in rodent macrophages in vitro. NO production and/or iNOS expression are also induced by inflammatory mediators in a wide variety of mammalian cells, producing large amounts of NO for prolonged time periods [25] . iNOS catalises the production of large amount of NO from L-arginine and molecular oxygen, is mainly triggered and regulated by a series of signalling pathways including nuclear factor-κB (NF-κB) transcription factor and mitogen-activated protein kinases (MAPKs) [116] .

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