Selected article for: "amino acid and deep sequencing"
Author: Barzon, Luisa; Lavezzo, Enrico; Militello, Valentina; Toppo, Stefano; Palù, Giorgio
Title: Applications of Next-Generation Sequencing Technologies to Diagnostic Virology
  • Document date: 2011_11_14
    • ID: 01nuj0lk_35
    Snippet: Analysis of full-length viral genome and quasispecies was also applied to other RNA viruses. Deep sequencing with the Illumina platform on total RNAs extracted from the lung of a patient who died of viral pneumonia due to pandemic 2009 influenza A virus (A/H1N1/2009) revealed nucleotide heterogeneity on hemagglutinin as quasispecies, leading to amino acid changes on antigenic sites which could be relevant for antigenic drift [31] ......
    Document: Analysis of full-length viral genome and quasispecies was also applied to other RNA viruses. Deep sequencing with the Illumina platform on total RNAs extracted from the lung of a patient who died of viral pneumonia due to pandemic 2009 influenza A virus (A/H1N1/2009) revealed nucleotide heterogeneity on hemagglutinin as quasispecies, leading to amino acid changes on antigenic sites which could be relevant for antigenic drift [31] .

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