Author: Hashem, Anwar M.; Flaman, Anathea S.; Farnsworth, Aaron; Brown, Earl G.; Van Domselaar, Gary; He, Runtao; Li, Xuguang
Title: Aurintricarboxylic Acid Is a Potent Inhibitor of Influenza A and B Virus Neuraminidases Document date: 2009_12_17
ID: 13bvkj2t_1
Snippet: Influenza viruses cause a highly contagious respiratory tract infection. The frequent mutations of influenza genes, particularly those encoding surface hemagglutinin (HA) and neuraminidase (NA) proteins, allow the virus to evade the host immune system. This gives rise to new infectious strains responsible for annual epidemics associated with significant morbidity and mortality [1, 2] . The recent infections of humans with the highly pathogenic av.....
Document: Influenza viruses cause a highly contagious respiratory tract infection. The frequent mutations of influenza genes, particularly those encoding surface hemagglutinin (HA) and neuraminidase (NA) proteins, allow the virus to evade the host immune system. This gives rise to new infectious strains responsible for annual epidemics associated with significant morbidity and mortality [1, 2] . The recent infections of humans with the highly pathogenic avian H5N1 [3] and swine-origin H1N1 [4] influenza viruses reinforce the notion that the emergence of novel virus strains is unpredictable and capable of threatening the worldwide population [5] . Given the magnitude of a flu pandemic as a threat to the global population, it is crucial to have as many prevention and treatment options as possible.
Search related documents:
Co phrase search for related documents- annual epidemic and Influenza virus: 1, 2, 3, 4, 5, 6, 7, 8
- annual epidemic and novel virus: 1
- annual epidemic and recent infection: 1
- annual epidemic and respiratory tract: 1, 2, 3
- annual epidemic and respiratory tract infection: 1
- flu pandemic and global population: 1, 2, 3
- flu pandemic and immune system: 1
- flu pandemic and influenza gene: 1
- flu pandemic and Influenza virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48
- flu pandemic and NA protein: 1
- flu pandemic and neuraminidase NA protein: 1
- flu pandemic and novel virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- flu pandemic and novel virus strain: 1
- flu pandemic and recent infection: 1
- flu pandemic and respiratory tract: 1, 2, 3
- flu pandemic and swine origin: 1
- flu pandemic and treatment prevention: 1, 2, 3, 4, 5, 6
- flu pandemic and worldwide population: 1
- frequent mutation and global population: 1, 2
Co phrase search for related documents, hyperlinks ordered by date