Author: Barzon, Luisa; Lavezzo, Enrico; Militello, Valentina; Toppo, Stefano; Palù, Giorgio
Title: Applications of Next-Generation Sequencing Technologies to Diagnostic Virology Document date: 2011_11_14
ID: 01nuj0lk_11
Snippet: A similar strategy, based on unbiased high-throughput sequencing using 454 pyrosequencing for the direct diagnosis of viral infections in clinical specimens, has been used in different diagnostic settings, such as the investigation of patients during seasonal influenza and norovirus outbreaks [22] , the identification of an astrovirus as a causative agent for encephalitis in a boy with agammaglobulinemia, after conventional methods had failed to .....
Document: A similar strategy, based on unbiased high-throughput sequencing using 454 pyrosequencing for the direct diagnosis of viral infections in clinical specimens, has been used in different diagnostic settings, such as the investigation of patients during seasonal influenza and norovirus outbreaks [22] , the identification of an astrovirus as a causative agent for encephalitis in a boy with agammaglobulinemia, after conventional methods had failed to identify an infectious agent [23] , and the identification of a hemorrhagic fever-associated arenavirus from South Africa (Lujo virus) [24] .
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