Author: Barzon, Luisa; Lavezzo, Enrico; Militello, Valentina; Toppo, Stefano; Palù, Giorgio
Title: Applications of Next-Generation Sequencing Technologies to Diagnostic Virology Document date: 2011_11_14
ID: 01nuj0lk_54
Snippet: As concerns the data analysis step, a multitude of software has been developed for very different applications of NGS. Nevertheless, if on the one hand this availability of methods greatly eases the task, on the other hand available algorithms for both genome assembly and amplicon analysis present limitations or drawbacks [137] which require custom made scripting and in-house resolution of bioinformatics problems caused by specific needs [46] . T.....
Document: As concerns the data analysis step, a multitude of software has been developed for very different applications of NGS. Nevertheless, if on the one hand this availability of methods greatly eases the task, on the other hand available algorithms for both genome assembly and amplicon analysis present limitations or drawbacks [137] which require custom made scripting and in-house resolution of bioinformatics problems caused by specific needs [46] . The direct consequence is that data analysis can be no more sustained by the wet-lab researcher alone, but requires the acquisition of computer skills and bioinformatics expertise.
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