Author: Wang, Kai; Ran, Ling; Yan, Tao; Niu, Zheng; Kan, Zifei; Zhang, Yiling; Yang, Yang; Xie, Luyi; Huang, Shilei; Yu, Qiuhan; Wu, Di; Song, Zhenhui
Title: Anti-TGEV Miller Strain Infection Effect of Lactobacillus plantarum Supernatant Based on the JAK-STAT1 Signaling Pathway Document date: 2019_11_6
ID: 05tf6oqa_50
Snippet: antigen presenting cells (APC), and enhance the molecular expression of MHC-II and IL-1β (Villena et al., 2014) . In addition, other lactic acid bacteria can also stimulate the response level of TLR-3 to poly (I: C) (Hosoya et al., 2011) . They can also regulate the role of TLR-2, TLR-4, and TLR negative regulators in the immune response, further enhancing the production of IFN-I induced by cells, and upregulate the transcription level of relate.....
Document: antigen presenting cells (APC), and enhance the molecular expression of MHC-II and IL-1β (Villena et al., 2014) . In addition, other lactic acid bacteria can also stimulate the response level of TLR-3 to poly (I: C) (Hosoya et al., 2011) . They can also regulate the role of TLR-2, TLR-4, and TLR negative regulators in the immune response, further enhancing the production of IFN-I induced by cells, and upregulate the transcription level of related antiviral factors (such as MXA and OASL) (Castillo et al., 2011) . Other studies have shown that probiotics can inhibit TGEV infection by adsorbing virus particles and stimulating cells to produce innate immunity (Chai et al., 2013) .
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