Author: Elsie Yekwa; Chutima Aphibanthammakit; Xavier Carnec; Bruno Coutard; Caroline Picard; Bruno Canard; Sylvain Baize; François Ferron
Title: Arenaviridae exoribonuclease presents genomic RNA edition capacity Document date: 2019_2_8
ID: fvp45ho6_32
Snippet: To assess the possible role of the NP-exo activity in viral replication and/or genome stability, we passaged iteratively 10 times in Vero E6 cells at a MOI of 0.01 a NP-exo defective virus (NP-exo(-))carrying the D390A/G393A mutants as well as a NP-exo WT recombinant MOPV......
Document: To assess the possible role of the NP-exo activity in viral replication and/or genome stability, we passaged iteratively 10 times in Vero E6 cells at a MOI of 0.01 a NP-exo defective virus (NP-exo(-))carrying the D390A/G393A mutants as well as a NP-exo WT recombinant MOPV.
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