Author: Elsie Yekwa; Chutima Aphibanthammakit; Xavier Carnec; Bruno Coutard; Caroline Picard; Bruno Canard; Sylvain Baize; François Ferron
Title: Arenaviridae exoribonuclease presents genomic RNA edition capacity Document date: 2019_2_8
ID: fvp45ho6_38
Snippet: We observe that the overall mutation rate is stable between NP-exo WT and NP-exo(-) MOPV, yet we also notice that the frequency of these mutations has changed. We observe at passage 10 a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/541698 doi: bioRxiv preprint %) for the WT and of ~ 16.6 % (comprised between 5 to 93 %) for the mutant, in particular the substitution of C to T. While for the .....
Document: We observe that the overall mutation rate is stable between NP-exo WT and NP-exo(-) MOPV, yet we also notice that the frequency of these mutations has changed. We observe at passage 10 a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/541698 doi: bioRxiv preprint %) for the WT and of ~ 16.6 % (comprised between 5 to 93 %) for the mutant, in particular the substitution of C to T. While for the S segment mutations appear along the entire for the WT and clustered for the mutant at respective frequencies of 14.6 % and 19.5 %.
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