Author: Carabineiro, Sónia Alexandra Correia
Title: Applications of Gold Nanoparticles in Nanomedicine: Recent Advances in Vaccines † Document date: 2017_5_22
ID: 0nz0qioh_42
Snippet: The use of gold nanoparticles in designing vaccines against tick-borne encephalitis (TBE) was proposed for the first time by Demenev et al. [103] . The vaccine was prepared by conjugating colloid gold with a soluble TBE antigen. In animals immunized with the experimental vaccine, the protection coefficient and mean survival time were, respectively, 1.3-1.5 times and 10-30% higher than in mice immunized with a commercial vaccine. Moreover, the mea.....
Document: The use of gold nanoparticles in designing vaccines against tick-borne encephalitis (TBE) was proposed for the first time by Demenev et al. [103] . The vaccine was prepared by conjugating colloid gold with a soluble TBE antigen. In animals immunized with the experimental vaccine, the protection coefficient and mean survival time were, respectively, 1.3-1.5 times and 10-30% higher than in mice immunized with a commercial vaccine. Moreover, the mean survival time was 1.2-1.7 times longer in animals injected with antibodies from mice immunized with the experimental vaccine, compared with the commercial one.
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