Selected article for: "candidate vaccine and disease agent"
Author: Carabineiro, Sónia Alexandra Correia
Title: Applications of Gold Nanoparticles in Nanomedicine: Recent Advances in Vaccines †
  • Document date: 2017_5_22
    • ID: 0nz0qioh_63
    Snippet: Burkholderia mallei are bacteria responsible for the glanders disease, which is recently classified as a Tier 1 agent, since they can be weaponized for aerosol release, cause high mortality rates, and show multi-drug resistance, and for which there is so far no vaccine available [128] . Gold nanoparticles were covalently coupled with one of three different protein carriers (TetHc, Hcp1, and FliC) followed by conjugation to lipopolysaccharide (LPS.....
    Document: Burkholderia mallei are bacteria responsible for the glanders disease, which is recently classified as a Tier 1 agent, since they can be weaponized for aerosol release, cause high mortality rates, and show multi-drug resistance, and for which there is so far no vaccine available [128] . Gold nanoparticles were covalently coupled with one of three different protein carriers (TetHc, Hcp1, and FliC) followed by conjugation to lipopolysaccharide (LPS) generated significantly higher antibody titers compared with LPS alone. In another study, a gold nanoparticle glycoconjugate composed of Burkholderia thailandensis LPS conjugated to FliC was evaluated for the first time as a candidate vaccine for glanders on rhesus macaques (Macaca mulatta) [57] .

    Search related documents:
    Co phrase search for related documents
    • antibody titer and gold nanoparticle: 1
    • antibody titer and high mortality: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • antibody titer and high mortality rate: 1, 2, 3
    • antibody titer and protein carrier: 1, 2, 3, 4
    • antibody titer and rhesus macaque: 1
    • antibody titer and significantly high antibody titer: 1
    • candidate vaccine and high mortality: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37
    • candidate vaccine and high mortality rate: 1, 2, 3, 4, 5, 6, 7, 8
    • candidate vaccine and protein carrier: 1, 2, 3, 4, 5
    • candidate vaccine and rhesus macaque: 1, 2, 3, 4, 5
    • high mortality and multi drug resistance: 1, 2, 3, 4