Selected article for: "respiratory tract and viral detection"
Author: Barzon, Luisa; Lavezzo, Enrico; Militello, Valentina; Toppo, Stefano; Palù, Giorgio
Title: Applications of Next-Generation Sequencing Technologies to Diagnostic Virology
  • Document date: 2011_11_14
    • ID: 01nuj0lk_13
    Snippet: Besides 454 pyrosequencing, short-read-based metagenomic methods using the Illumina GA platform have also been used to detect unknown viruses in clinical specimens. The Illumina GA platform allowed to identify influenza A viruses from swab specimens and de novo assembly of its genome [30] [31] [32] . It also led to the detection of viral pathogens in nasopharyngeal aspirate samples from patients with acute lower respiratory tract infections [33] .....
    Document: Besides 454 pyrosequencing, short-read-based metagenomic methods using the Illumina GA platform have also been used to detect unknown viruses in clinical specimens. The Illumina GA platform allowed to identify influenza A viruses from swab specimens and de novo assembly of its genome [30] [31] [32] . It also led to the detection of viral pathogens in nasopharyngeal aspirate samples from patients with acute lower respiratory tract infections [33] , such as a new enterovirus, named enterovirus 109 (EV109) detected in a cohort of Nicaraguan children with viral respiratory illness [34] .

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