Author: Saeed, Abdullah F. U. H.; Wang, Rongzhi; Ling, Sumei; Wang, Shihua
Title: Antibody Engineering for Pursuing a Healthier Future Document date: 2017_3_28
ID: 0fegsm1v_35
Snippet: MAb-based products exhibit superior specificity for a particular antigen. This characteristic feature of the immunoglobins makes them an ideal tool for many applications including disease diagnosis and therapy ( Table 2 ; Modjtahedi et al., 2012; Redman et al., 2015; Steplewski et al., 2015) . Diagnostic applications include biochemical analysis and imaging. It involves a number of immunoassays for the detection of hormonal, tissue, and cell prod.....
Document: MAb-based products exhibit superior specificity for a particular antigen. This characteristic feature of the immunoglobins makes them an ideal tool for many applications including disease diagnosis and therapy ( Table 2 ; Modjtahedi et al., 2012; Redman et al., 2015; Steplewski et al., 2015) . Diagnostic applications include biochemical analysis and imaging. It involves a number of immunoassays for the detection of hormonal, tissue, and cell products. Imaging is carried out using radiolabeled mAbs for diagnostics of infectious diseases. Therapeutic mAbs have a wide range of applications. They are used in the treatment of cancer, transplantation of bone marrow and organs, autoimmune diseases, cardiovascular diseases, and various infectious diseases. Targeting agents in therapy Toxins, drugs, radioisotopes etc., can be attached or conjugated to the tissue-specific mAbs and carried to target tissues for efficient action.
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