Author: Aran Singanayagam; Su-Ling Loo; Maria Calderazzo; Lydia J Finney; Maria-Belen Trujillo Torralbo; Eteri Bakhsoliani; Jason Girkin; Punnam Veerati; Prabuddha S Pathinayake; Kristy S Nichol; Andrew Reid; Joseph Foottit; Sebastian L Johnston; Nathan W Bartlett; Patrick Mallia
Title: Anti-microbial immunity is impaired in COPD patients with frequent exacerbations Document date: 2019_5_9
ID: 72jzqm86_9
Snippet: For baseline analyses of sputum soluble mediators, in addition to samples taken from the naturally occurring exacerbation study, we also included baseline (pre-infection) samples from 14 COPD subjects recruited to experimental challenge COPD studies 8, 18 . All subjects in these studies gave informed written consent and the protocol was approved by St Mary's NHS Trust Research Ethics Committee (study numbers 00/BA/459E and 07/H0712/138). These su.....
Document: For baseline analyses of sputum soluble mediators, in addition to samples taken from the naturally occurring exacerbation study, we also included baseline (pre-infection) samples from 14 COPD subjects recruited to experimental challenge COPD studies 8, 18 . All subjects in these studies gave informed written consent and the protocol was approved by St Mary's NHS Trust Research Ethics Committee (study numbers 00/BA/459E and 07/H0712/138). These subjects were characterised as frequent or infrequent exacerbators using the same definition as described above. Sputum samples were processed using exactly the same methodology as described in the naturally occurring exacerbation study. author/funder. All rights reserved. No reuse allowed without permission.
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