Selected article for: "antibody response and recombinant antigen"

Author: Carabineiro, Sónia Alexandra Correia
Title: Applications of Gold Nanoparticles in Nanomedicine: Recent Advances in Vaccines †
  • Document date: 2017_5_22
  • ID: 0nz0qioh_59
    Snippet: Gold nanoparticles were coated with the F1-antigen of Yersinia pestis (bacterium responsible for the plague), using N-hydroxysuccinimide and N-(3-dimethylaminopropyl)-N -ethylcarbodiimide hydrochloride coupling chemistry, and administrated to mice, triggering an IgG antibody response to the F1-antigen [124] . The sera raised against F1-antigen coupled to Au nanoparticles were able to competitively bind to recombinant F1-antigen, displacing protec.....
    Document: Gold nanoparticles were coated with the F1-antigen of Yersinia pestis (bacterium responsible for the plague), using N-hydroxysuccinimide and N-(3-dimethylaminopropyl)-N -ethylcarbodiimide hydrochloride coupling chemistry, and administrated to mice, triggering an IgG antibody response to the F1-antigen [124] . The sera raised against F1-antigen coupled to Au nanoparticles were able to competitively bind to recombinant F1-antigen, displacing protective macaque sera.

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