Author: Hermesh, Tamar; Moltedo, Bruno; López, Carolina B.; Moran, Thomas M.
Title: Buying Time—The Immune System Determinants of the Incubation Period to Respiratory Viruses Document date: 2010_11_18
ID: 0yqv2osb_26
Snippet: Similarly to type I IFNs, type III IFNs (IFN-λ), which in humans include IL-29, IL-28α and IL-28β, are expressed by many cell types after virus infection or TLR ligand stimulation and have similar effects to those observed with type I IFNs [55, 56] . The receptor for IFN-λ (IFN-λR) is composed by one IFN-λR chain and one IL-10Rβ chain. IFN-λR also signals through the JAK-STAT pathway [57] [58] [59] . Expression of IFN-λR appears to be re.....
Document: Similarly to type I IFNs, type III IFNs (IFN-λ), which in humans include IL-29, IL-28α and IL-28β, are expressed by many cell types after virus infection or TLR ligand stimulation and have similar effects to those observed with type I IFNs [55, 56] . The receptor for IFN-λ (IFN-λR) is composed by one IFN-λR chain and one IL-10Rβ chain. IFN-λR also signals through the JAK-STAT pathway [57] [58] [59] . Expression of IFN-λR appears to be restricted to non-hematopoietic cells such as epithelial cells.
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