Author: Chen, Shilong; Wang, Long; Chen, Jieying; Zhang, Lanlan; Wang, Song; Goraya, Mohsan U.; Chi, Xiaojuan; Na, Yang; Shao, Wenhan; Yang, Zhou; Zeng, Xiancheng; Chen, Shaoying; Chen, Ji-Long
Title: Avian Interferon-Inducible Transmembrane Protein Family Effectively Restricts Avian Tembusu Virus Infection Document date: 2017_4_20
ID: 0pjg25kn_32
Snippet: Since ATMUV infection induced significant upregulation of IFNs and IFITMs in vivo and in vitro, we asked whether increased IFITM expression was stimulated by ATMUV-induced IFNs in DF-1 cells. To this end, DF-1 cells were treated with chicken IFNs (500 IU/mL) and mRNA levels of IFITMs were examined by qRT-PCR. Indeed, we found that expression of IFITM1, 2, 3 was significantly upregulated in DF-1 cells after treatment with chicken IFNs (Figure 4G ).....
Document: Since ATMUV infection induced significant upregulation of IFNs and IFITMs in vivo and in vitro, we asked whether increased IFITM expression was stimulated by ATMUV-induced IFNs in DF-1 cells. To this end, DF-1 cells were treated with chicken IFNs (500 IU/mL) and mRNA levels of IFITMs were examined by qRT-PCR. Indeed, we found that expression of IFITM1, 2, 3 was significantly upregulated in DF-1 cells after treatment with chicken IFNs (Figure 4G ).
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