Author: Yong, Kylie Su Mei; Ng, Justin Han Jia; Her, Zhisheng; Hey, Ying Ying; Tan, Sue Yee; Tan, Wilson Wei Sheng; Irac, Sergio Erdal; Liu, Min; Chan, Xue Ying; Gunawan, Merry; Foo, Randy Jee Hiang; Low, Dolyce Hong Wen; Mendenhall, Ian Hewitt; Chionh, Yok Teng; Dutertre, Charles-Antoine; Chen, Qingfeng; Wang, Lin-Fa
Title: Bat-mouse bone marrow chimera: a novel animal model for dissecting the uniqueness of the bat immune system Document date: 2018_3_16
ID: 01f36rld_23
Snippet: Mice. NOD-scid IL2Rγ −/− (NSG) mice (Stock #005557) were obtained from Jackson Laboratory and bred in the animal facility at A*STAR, Biological Resource Centre. Neonatal mice (100 rads), within 72 hours of birth, and 8-week old adult mice (250 rads) were sub-lethally irradiated and injected with bat cells via intra-hepatic 61 and intra-venous injection, respectively. The International Animal Care and Use Committee (IACUC), A*STAR approved th.....
Document: Mice. NOD-scid IL2Rγ −/− (NSG) mice (Stock #005557) were obtained from Jackson Laboratory and bred in the animal facility at A*STAR, Biological Resource Centre. Neonatal mice (100 rads), within 72 hours of birth, and 8-week old adult mice (250 rads) were sub-lethally irradiated and injected with bat cells via intra-hepatic 61 and intra-venous injection, respectively. The International Animal Care and Use Committee (IACUC), A*STAR approved this study and assigned a protocol number (BRC #151039). All animal experimental procedures carried out were in accordance to the protocol's guidelines and regulations.
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