Author: Fallahi, Poupak; Ferrari, Silvia Martina; Politti, Ugo; Giuggioli, Dilia; Ferri, Clodoveo; Antonelli, Alessandro
Title: Autoimmune and Neoplastic Thyroid Diseases Associated with Hepatitis C Chronic Infection Document date: 2014_10_13
ID: 0go1vl9q_3
Snippet: An association between HCV and mixed cryoglobulinemia (MC) was first described; subsequently, the involvement of many organs and systems was reported (kidney, skin, eyes, joints, and nervous system). The infected extrahepatic tissues might act as a reservoir for HCV [5] and play a role in both HCV persistence and reactivation of infection. HCV, as an etiological agent replicating and expressing viral proteins in extrahepatic tissues itself, contr.....
Document: An association between HCV and mixed cryoglobulinemia (MC) was first described; subsequently, the involvement of many organs and systems was reported (kidney, skin, eyes, joints, and nervous system). The infected extrahepatic tissues might act as a reservoir for HCV [5] and play a role in both HCV persistence and reactivation of infection. HCV, as an etiological agent replicating and expressing viral proteins in extrahepatic tissues itself, contributes to EHM associated with chronic HCV infection. An important feature of HCV is that the virus avoids immune elimination; a consequence is chronic infection and an accumulation of circulating immunocomplexes and autoimmune phenomena [6] [7] [8] , as recently Cheng et al. have demonstrated in their study among 297 Chinese patients [9] .
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