Selected article for: "antiviral drug and new antiviral drug"
Author: Barzon, Luisa; Lavezzo, Enrico; Militello, Valentina; Toppo, Stefano; Palù, Giorgio
Title: Applications of Next-Generation Sequencing Technologies to Diagnostic Virology
  • Document date: 2011_11_14
    • ID: 01nuj0lk_46
    Snippet: Finally, with the availability of new drugs targeting HCV protease and polymerase, the experience of drug-resistance mutation and quasispecies analysis achieved with HIV is being translated to HCV. Also for HCV, deep sequencing technologies seem a promising tool for the study of minority variants present in the HCV quasispecies population at baseline and during antiviral drug pressure, giving new insights into the dynamics of resistance acquisiti.....
    Document: Finally, with the availability of new drugs targeting HCV protease and polymerase, the experience of drug-resistance mutation and quasispecies analysis achieved with HIV is being translated to HCV. Also for HCV, deep sequencing technologies seem a promising tool for the study of minority variants present in the HCV quasispecies population at baseline and during antiviral drug pressure, giving new insights into the dynamics of resistance acquisition by HCV [126, 127] .

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