Selected article for: "clinical significance and human illness"
Author: Hu, Tingsong; Qiu, Wei; He, Biao; Zhang, Yan; Yu, Jing; Liang, Xiu; Zhang, Wendong; Chen, Gang; Zhang, Yingguo; Wang, Yiyin; Zheng, Ying; Feng, Ziliang; Hu, Yonghe; Zhou, Weiguo; Tu, Changchun; Fan, Quanshui; Zhang, Fuqiang
Title: Characterization of a novel orthoreovirus isolated from fruit bat, China
  • Document date: 2014_11_30
    • ID: 1fw9ng2p_15
    Snippet: The discovery of Melaka and Kampar viruses provide evidence that a novel group of fusogenic orthoreoviruses of bat origin are associated with acute respiratory disease in humans [9, 16] . To date, there have been six confirmed outbreaks of human respiratory illness caused by this group of viruses; three in Malaysia and three in Bali/Hong Kong [9, 16, 17, 19, 20] . Despite a lack of direct epidemiological and clinical evidence to support the novel.....
    Document: The discovery of Melaka and Kampar viruses provide evidence that a novel group of fusogenic orthoreoviruses of bat origin are associated with acute respiratory disease in humans [9, 16] . To date, there have been six confirmed outbreaks of human respiratory illness caused by this group of viruses; three in Malaysia and three in Bali/Hong Kong [9, 16, 17, 19, 20] . Despite a lack of direct epidemiological and clinical evidence to support the novel Cangyuan orthoreovirus of bat origin isolated in this study as a causative agent of human respiratory tract infections in China, the genetic relatedness between Cangyuan virus and the Melaka and Kampar viruses implies that it may be a zoonotic infectious agent of clinical significance to human health.

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