Selected article for: "apod function and molecular basis"
Author: Perdomo, German; Dong, H. Henry
Title: Apolipoprotein D in Lipid Metabolism and Its Functional Implication in Atherosclerosis and Aging
  • Document date: 2008_12_12
    • ID: 167z915s_20
    Snippet: In addition to its role in cholesterol homeostasis, apoD is involved in triglyceride metabolism. Epidemiological studies identified three distinct missense mutations, namely Phe36Val, Tyr108Cys and Thr158Lys in the apoD gene in African populations. Each of these three mutations is associated with significantly elevated plasma triglyceride levels and reduced HDL-cholesterol levels, a plasma lipid profile that is characteristic of metabolic syndrom.....
    Document: In addition to its role in cholesterol homeostasis, apoD is involved in triglyceride metabolism. Epidemiological studies identified three distinct missense mutations, namely Phe36Val, Tyr108Cys and Thr158Lys in the apoD gene in African populations. Each of these three mutations is associated with significantly elevated plasma triglyceride levels and reduced HDL-cholesterol levels, a plasma lipid profile that is characteristic of metabolic syndrome [52, 53] . Although the underlying molecular basis remains to be defined, these clinical data implicate abnormal apoD function in the pathogenesis of metabolic syndrome.

    Search related documents:
    Co phrase search for related documents
    • HDL cholesterol and molecular basis: 1
    • HDL cholesterol and plasma lipid: 1, 2, 3, 4, 5, 6, 7, 8
    • HDL cholesterol and plasma lipid profile: 1, 2, 3, 4, 5
    • HDL cholesterol and plasma triglyceride level: 1
    • HDL cholesterol and triglyceride level: 1, 2
    • HDL cholesterol and triglyceride metabolism: 1, 2
    • HDL cholesterol and underlying molecular basis: 1
    • HDL cholesterol level and triglyceride level: 1
    • molecular basis and underlying molecular basis: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
    • plasma lipid and triglyceride level: 1
    • plasma lipid and triglyceride metabolism: 1
    • plasma lipid profile and triglyceride level: 1
    • plasma triglyceride level and triglyceride level: 1, 2