Author: Hermesh, Tamar; Moltedo, Bruno; López, Carolina B.; Moran, Thomas M.
Title: Buying Time—The Immune System Determinants of the Incubation Period to Respiratory Viruses Document date: 2010_11_18
ID: 0yqv2osb_46
Snippet: The natural process by which viruses replicate may contribute to the culmination of the stealth phase. The viral polymerase of many of the viruses discussed here is error-prone. From an evolution or natural selection standpoint, this property has the advantage of promoting rapid mutations in the viral genome, avoiding recognition by the adaptive immune response. However, it is also possible that such a process promotes mistakes in viral replicati.....
Document: The natural process by which viruses replicate may contribute to the culmination of the stealth phase. The viral polymerase of many of the viruses discussed here is error-prone. From an evolution or natural selection standpoint, this property has the advantage of promoting rapid mutations in the viral genome, avoiding recognition by the adaptive immune response. However, it is also possible that such a process promotes mistakes in viral replication, such as the generation of mutated, less efficient viral antagonists and defective interfering virus particles (DIs) that may lead to immune recognition. It has been shown in mice that stocks of SeV with high DI content enhance the immune response [112] and MeV vaccine strains induction of type I IFNs correlates with high DI content [113] .
Search related documents:
Co phrase search for related documents- adaptive immune response and immune recognition: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- adaptive immune response and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82
- adaptive immune response and type induction: 1, 2, 3, 4, 5
- adaptive immune response and viral antagonist: 1
- adaptive immune response and viral genome: 1, 2, 3, 4, 5, 6
- adaptive immune response and viral polymerase: 1
- adaptive immune response and viral replication: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37
- adaptive immune response and virus particle: 1
- adaptive immune response and virus replicate: 1
- adaptive immune response recognition and immune recognition: 1, 2
- adaptive immune response recognition and immune response: 1, 2, 3, 4
- DI content and viral genome: 1
- discuss virus and immune recognition: 1
- discuss virus and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
Co phrase search for related documents, hyperlinks ordered by date