Author: Orwoll, Benjamin E.; Sapru, Anil
Title: Biomarkers in Pediatric ARDS: Future Directions Document date: 2016_6_1
ID: 0n5apnle_27
Snippet: As a mediator of vascular permeability, angiopoeitin-2 (Ang-2) may play a significant role in the development of and outcomes from ARDS (155) . In adults with ARDS, Ang-2 levels in the plasma are elevated compared with controls and predict mortality in medical and trauma-related ARDS (83, (156) (157) (158) . Though data remain relatively sparse among pediatric patients, we recently reported that Ang-2 elevations are associated with mortality in p.....
Document: As a mediator of vascular permeability, angiopoeitin-2 (Ang-2) may play a significant role in the development of and outcomes from ARDS (155) . In adults with ARDS, Ang-2 levels in the plasma are elevated compared with controls and predict mortality in medical and trauma-related ARDS (83, (156) (157) (158) . Though data remain relatively sparse among pediatric patients, we recently reported that Ang-2 elevations are associated with mortality in pARDS and, additionally, that rising Ang-2 levels are highly predictive of mortality among hematopoietic stem cell transplant recipients (40) .
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