Author: Orwoll, Benjamin E.; Sapru, Anil
Title: Biomarkers in Pediatric ARDS: Future Directions Document date: 2016_6_1
ID: 0n5apnle_28
Snippet: The endothelium, with its diverse functions involving, among others, inflammation, coagulation, and hemodynamics, has a central role in the pathobiology of ARDS in children. Markers, such as vWF, selectins, ET-1, sTM, and Ang-2, are associated with the endothelium in ARDS, each with a different functional implication. Clinical assessments of these markers will help construct a more complete view of the endothelial function and guide future therap.....
Document: The endothelium, with its diverse functions involving, among others, inflammation, coagulation, and hemodynamics, has a central role in the pathobiology of ARDS in children. Markers, such as vWF, selectins, ET-1, sTM, and Ang-2, are associated with the endothelium in ARDS, each with a different functional implication. Clinical assessments of these markers will help construct a more complete view of the endothelial function and guide future therapeutic trials.
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