Author: Carabineiro, Sónia Alexandra Correia
Title: Applications of Gold Nanoparticles in Nanomedicine: Recent Advances in Vaccines † Document date: 2017_5_22
ID: 0nz0qioh_27
Snippet: Identification of tumor-associated antigens (TAAs) and tumor-specific antigens (TSAs) has led to increased efforts to develop vaccination strategies. Vaccines may be composed of whole cells or cell extracts, genetically modified tumor cells, dendritic cells (DCs) loaded with TAAs, immunization with soluble proteins or synthetic peptides, recombinant viruses or bacteria encoding tumor-associated antigens, and plasmid DNA-encoding TSAs or TAAs in c.....
Document: Identification of tumor-associated antigens (TAAs) and tumor-specific antigens (TSAs) has led to increased efforts to develop vaccination strategies. Vaccines may be composed of whole cells or cell extracts, genetically modified tumor cells, dendritic cells (DCs) loaded with TAAs, immunization with soluble proteins or synthetic peptides, recombinant viruses or bacteria encoding tumor-associated antigens, and plasmid DNA-encoding TSAs or TAAs in conjunction with appropriate immunomodulators [32, 79] . All of these vaccination approaches aim to induce specific immunological responses and are localized into TAAs, destroying only the tumor cells and leaving the majority of other cells of the body undamaged.
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