Author: Hijano, Diego R.; Brazelton de Cardenas, Jessica; Maron, Gabriela; Garner, Cherilyn D.; Ferrolino, Jose A.; Dallas, Ronald H.; Gu, Zhengming; Hayden, Randall T.
Title: Clinical correlation of influenza and respiratory syncytial virus load measured by digital PCR Document date: 2019_9_3
ID: 1sli4e5v_21
Snippet: https://doi.org/10.1371/journal.pone.0220908.g002 Viral respiratory load by digital PCR initially positive in BioFire FilmArray 1 analysis, 19 (13.86%) were below the established limit of quantification by dPCR and were considered negative: 2 (8.0%) for influenza A, 7 (17.95%) for influenza B, and 10 (13.69%) for RSV. All these corresponded to samples obtained after antiviral treatment was completed. For samples included in the validation, the sp.....
Document: https://doi.org/10.1371/journal.pone.0220908.g002 Viral respiratory load by digital PCR initially positive in BioFire FilmArray 1 analysis, 19 (13.86%) were below the established limit of quantification by dPCR and were considered negative: 2 (8.0%) for influenza A, 7 (17.95%) for influenza B, and 10 (13.69%) for RSV. All these corresponded to samples obtained after antiviral treatment was completed. For samples included in the validation, the specificity for influenza A was 82.05%, influenza B, 100%, and RSV was 86.66%. The clinical sensitivity was 92% for influenza A, 82.05% for influenza B, and 86.30% for RSV.
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