Author: Perra, Léa; Balloy, Viviane; Foussignière, Tobias; Moissenet, Didier; Petat, Hortense; Mungrue, Imran N.; Touqui, Lhousseine; Corvol, Harriet; Chignard, Michel; Guillot, Loic
Title: CHAC1 Is Differentially Expressed in Normal and Cystic Fibrosis Bronchial Epithelial Cells and Regulates the Inflammatory Response Induced by Pseudomonas aeruginosa Document date: 2018_11_29
ID: 10fe70kl_24
Snippet: We further validated the differential expression of CHAC1 by qPCR in the same samples used for RNA-seq. Indeed, at baseline, we observed significantly higher expression of CHAC1 in non-CF cells compared with that in CF cells. As expected from the transcriptomic data, we observed upregulation of CHAC1 mRNA expression after 6 h of Pa infection only in non-CF cells ( Figure 1B )......
Document: We further validated the differential expression of CHAC1 by qPCR in the same samples used for RNA-seq. Indeed, at baseline, we observed significantly higher expression of CHAC1 in non-CF cells compared with that in CF cells. As expected from the transcriptomic data, we observed upregulation of CHAC1 mRNA expression after 6 h of Pa infection only in non-CF cells ( Figure 1B ).
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