Author: Wang, Xiaona; Li, Fengsai; Han, Meijing; Jia, Shuo; Wang, Li; Qiao, Xinyuan; Jiang, Yanping; Cui, Wen; Tang, Lijie; Li, Yijing; Xu, Yi-Gang
Title: Cloning, Prokaryotic Soluble Expression, and Analysis of Antiviral Activity of Two Novel Feline IFN-? Proteins Document date: 2020_3_19
ID: 1me7ugkg_27
Snippet: We determined the antiviral activity of rfeIFN-ωa and rfeIFN-ωb using microdose cytopathic effect inhibition assays (MCIAs) and VSV as the viral model that was propagated on F81 cells. As shown in Figure 5 , both rfeIFN-ωa and rfeIFN-ωb demonstrated good antiviral activity similar to the INTERCAT IFN (feline IFN antiviral drug) positive control. However, no antiviral effect in negative control groups (cells untreated with the IFNs) was detect.....
Document: We determined the antiviral activity of rfeIFN-ωa and rfeIFN-ωb using microdose cytopathic effect inhibition assays (MCIAs) and VSV as the viral model that was propagated on F81 cells. As shown in Figure 5 , both rfeIFN-ωa and rfeIFN-ωb demonstrated good antiviral activity similar to the INTERCAT IFN (feline IFN antiviral drug) positive control. However, no antiviral effect in negative control groups (cells untreated with the IFNs) was detected.
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