Author: Lau, Yee-Ling; Lai, Meng-Yee; Teoh, Boon-Teong; Abd-Jamil, Juraina; Johari, Jefree; Sam, Sing-Sin; Tan, Kim-Kee; AbuBakar, Sazaly
Title: Colorimetric Detection of Dengue by Single Tube Reverse-Transcription-Loop-Mediated Isothermal Amplification Document date: 2015_9_18
ID: 1946zslt_2
Snippet: Currently available diagnostic tests used for dengue diagnosis in most dengue-endemic countries include commercially available IgM-and IgG-based ELISAs. These assays use dengue-specific antigens from all 4 serotypes (DENV [1] [2] [3] [4] and are designed to capture anti-dengue specific antibodies present in serum. However, serology tests are usually inconsistent since detection of antibodies requires appropriate collection times and test results .....
Document: Currently available diagnostic tests used for dengue diagnosis in most dengue-endemic countries include commercially available IgM-and IgG-based ELISAs. These assays use dengue-specific antigens from all 4 serotypes (DENV [1] [2] [3] [4] and are designed to capture anti-dengue specific antibodies present in serum. However, serology tests are usually inconsistent since detection of antibodies requires appropriate collection times and test results may be confused with false-positive reactions due to the presence of antibodies from previous infections.
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