Author: Manandhar, Bandana; Paudel, Pradeep; Seong, Su Hui; Jung, Hyun Ah; Choi, Jae Sue
Title: Characterizing Eckol as a Therapeutic Aid: A Systematic Review Document date: 2019_6_18
ID: 0dpv85od_149
Snippet: Eckol was isolated from Ecklonia kurome to evaluate the structural requirements necessary for inhibition of α 2 macroglobulin (α 2 -M) and α 2 plasmin (α 2 -P) inhibitors. The main plasmin inhibitors in plasma include the α 2 -M and α 2 -P inhibitors. Eckol exhibited potent and specific inhibitory activity on the actions of α 2 -M (IC 50 2.5 µg/mL) and α 2 -P (IC 50 1.6 µg/mL). The synthesis of various methylated derivatives of eckol in.....
Document: Eckol was isolated from Ecklonia kurome to evaluate the structural requirements necessary for inhibition of α 2 macroglobulin (α 2 -M) and α 2 plasmin (α 2 -P) inhibitors. The main plasmin inhibitors in plasma include the α 2 -M and α 2 -P inhibitors. Eckol exhibited potent and specific inhibitory activity on the actions of α 2 -M (IC 50 2.5 µg/mL) and α 2 -P (IC 50 1.6 µg/mL). The synthesis of various methylated derivatives of eckol in this study and their inhibitory activity on the anti-plasmins implied that a simple dibenzo-1,4-dioxin skeleton bearing some functional groups could become a lead compound in the development of a new class of thrombolytic agents [120] .
Search related documents:
Co phrase search for related documents- µg ml and inhibitory activity: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- µg ml and lead compound: 1, 2
- µg ml and new class: 1, 2, 3, 4, 5, 6, 7
- µg ml and study eckol: 1, 2
- anti plasmin and inhibitory activity: 1
- anti plasmin and study eckol: 1
- functional group and inhibitory activity: 1
- functional group and new class: 1
- inhibitory activity and lead compound: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- inhibitory activity and study eckol: 1
- lead compound and new class: 1, 2
Co phrase search for related documents, hyperlinks ordered by date