Author: Bernard-Stoecklin, Sibylle; Nikolay, Birgit; Assiri, Abdullah; Bin Saeed, Abdul Aziz; Ben Embarek, Peter Karim; El Bushra, Hassan; Ki, Moran; Malik, Mamunur Rahman; Fontanet, Arnaud; Cauchemez, Simon; Van Kerkhove, Maria D.
Title: Comparative Analysis of Eleven Healthcare-Associated Outbreaks of Middle East Respiratory Syndrome Coronavirus (Mers-Cov) from 2015 to 2017 Document date: 2019_5_14
ID: 1t3hg4wi_23
Snippet: Risk factors associated with fatal outcome. In univariate analysis, fatal outcome was significantly associated with age (p < 0.001), presence of underlying comorbidities (p < 0.001), non-HCP status (p < 0.001), and male sex (p < 0.001, Estimation of time-varying reproduction number. At the start of each HCA outbreaks, the case reproduction number R (t) ranged from 1.0 (95% CI 0.7-1.3) to 5.7 (95% CI 3.0-9.0) ( Table 1 and Fig. 2 ). Estimates of R.....
Document: Risk factors associated with fatal outcome. In univariate analysis, fatal outcome was significantly associated with age (p < 0.001), presence of underlying comorbidities (p < 0.001), non-HCP status (p < 0.001), and male sex (p < 0.001, Estimation of time-varying reproduction number. At the start of each HCA outbreaks, the case reproduction number R (t) ranged from 1.0 (95% CI 0.7-1.3) to 5.7 (95% CI 3.0-9.0) ( Table 1 and Fig. 2 ). Estimates of R (t) dropped below 1 within 2 to 6 weeks from the first reported case in the outbreak (n = 11 outbreaks, median 3 weeks, IQR 2-4).
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