Author: Geng, Lingling; Liu, Zunpeng; Zhang, Weiqi; Li, Wei; Wu, Zeming; Wang, Wei; Ren, Ruotong; Su, Yao; Wang, Peichang; Sun, Liang; Ju, Zhenyu; Chan, Piu; Song, Moshi; Qu, Jing; Liu, Guang-Hui
Title: Chemical screen identifies a geroprotective role of quercetin in premature aging Document date: 2018_8_1
ID: 1mrj6nb3_73
Snippet: Transcription levels of aging-and longevity-associated genes as well as the NRF2 target genes were analyzed as below. The agingand longevity-associated genes were identified according to the Human Ageing Genomic Resources (HAGR) database and NRF2 target genes from the C3 transcription factor targets in Molecular Signatures Database v6.0 (MSigDB, GSEA) with the addition of other NRF2 genes that have been previously reported (Kubben et al., 2016; R.....
Document: Transcription levels of aging-and longevity-associated genes as well as the NRF2 target genes were analyzed as below. The agingand longevity-associated genes were identified according to the Human Ageing Genomic Resources (HAGR) database and NRF2 target genes from the C3 transcription factor targets in Molecular Signatures Database v6.0 (MSigDB, GSEA) with the addition of other NRF2 genes that have been previously reported (Kubben et al., 2016; Reszka et al., 2015; Tacutu et al., 2013) . Genes with an adjust P value (Benjamini-Hochberg) less than 0.05 were analyzed and P values were calculated by Two-sample Kolmogorov-Smirnov test.
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