Author: Russell, Beth; Moss, Charlotte; Rigg, Anne; Van Hemelrijck, Mieke
Title: COVID-19 and treatment with NSAIDs and corticosteroids: should we be limiting their use in the clinical setting? Document date: 2020_3_30
ID: 0uengr9t_3
Snippet: Across Europe, the incidence and mortality rates of COVID-19 or severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) continue to rise dramatically. The disease is named due to the similarities to the SARS outbreak in China of 2002, which was also caused by a coronavirus. However, SARS-CoV-2 is thought to be caused by a novel coronavirus not seen before. Alongside uncertainty related to infection aetiology and outcomes, emerging concerns .....
Document: Across Europe, the incidence and mortality rates of COVID-19 or severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) continue to rise dramatically. The disease is named due to the similarities to the SARS outbreak in China of 2002, which was also caused by a coronavirus. However, SARS-CoV-2 is thought to be caused by a novel coronavirus not seen before. Alongside uncertainty related to infection aetiology and outcomes, emerging concerns relate to the use of common non-steroidal anti-inflammatory drugs (NSAIDs) and corticosteroids. The Belgian Federal Agency for Medicines and Health Products released a statement on 16th March 2020 stating 'It is well known that NSAIDs and corticosteroids can lead to serious complications'. Equally, a report by French Authorities suggested the use of ibuprofen in COVID-19 patients was detrimental to patient condition and recovery. NSAIDs are often used for the management of mild pain in cancer patients; hence, this topic is of particular importance to these patients. We, therefore, sought to gather information on the use of NSAIDs or corticosteroids and COVID-19, through systematic review of existing literature.
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