Author: Zhu, Zheng; Chan, Jasper Fuk-Woo; Tee, Kah-Meng; Choi, Garnet Kwan-Yue; Lau, Susanna Kar-Pui; Woo, Patrick Chiu-Yat; Tse, Herman; Yuen, Kwok-Yung
Title: Comparative genomic analysis of pre-epidemic and epidemic Zika virus strains for virological factors potentially associated with the rapidly expanding epidemic Document date: 2016_3_16
ID: 1hmte4la_10
Snippet: RNA secondary structures and cyclization elements A Y-shape stem-loop A (SLA) structure is found at the 5ʹ-end of the ZIKV genome ( Figure 5 ). At the 3ʹ-end of the viral genome, a small hairpin 3ʹ-stem-loop (sHP-3ʹ SL) structure, three additional SL structures, and a dumbbell (DB) structure are found. Notably, the external loop of the SLI in domain 1 of the 3ʹ-UTR just distal to the stop codon of the NS5 in the 1947 prototype pre-epidemic s.....
Document: RNA secondary structures and cyclization elements A Y-shape stem-loop A (SLA) structure is found at the 5ʹ-end of the ZIKV genome ( Figure 5 ). At the 3ʹ-end of the viral genome, a small hairpin 3ʹ-stem-loop (sHP-3ʹ SL) structure, three additional SL structures, and a dumbbell (DB) structure are found. Notably, the external loop of the SLI in domain 1 of the 3ʹ-UTR just distal to the stop codon of the NS5 in the 1947 prototype pre-epidemic strain is
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