Author: Bernard-Stoecklin, Sibylle; Nikolay, Birgit; Assiri, Abdullah; Bin Saeed, Abdul Aziz; Ben Embarek, Peter Karim; El Bushra, Hassan; Ki, Moran; Malik, Mamunur Rahman; Fontanet, Arnaud; Cauchemez, Simon; Van Kerkhove, Maria D.
Title: Comparative Analysis of Eleven Healthcare-Associated Outbreaks of Middle East Respiratory Syndrome Coronavirus (Mers-Cov) from 2015 to 2017 Document date: 2019_5_14
ID: 1t3hg4wi_35
Snippet: Our study has several limitations due to variability in the completeness and quality of case-based data provided to WHO since 2012 and also due to the lack of detailed information on the timing specific interventions were implemented in relation to each outbreak. Without detailed information on the timing of interventions in each health care facility it was not possible in our analyses to determine which intervention or combination of interventio.....
Document: Our study has several limitations due to variability in the completeness and quality of case-based data provided to WHO since 2012 and also due to the lack of detailed information on the timing specific interventions were implemented in relation to each outbreak. Without detailed information on the timing of interventions in each health care facility it was not possible in our analyses to determine which intervention or combination of interventions had the greatest impact on stopping the MERS outbreaks. Moreover, prior to 2015, contacts without symptoms were not tested for MERS-CoV infection, thus the rate of identification of secondary cases was drastically different prior to 2015, which complicates the comparison of data collected before and after 2015. The improvements in data reporting on cases (e.g., more systematic reporting of underlying conditions, reported exposures, contacts between patients) from 2015 allowed us to perform better analyses with less missing values.
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