Author: Hijano, Diego R.; Brazelton de Cardenas, Jessica; Maron, Gabriela; Garner, Cherilyn D.; Ferrolino, Jose A.; Dallas, Ronald H.; Gu, Zhengming; Hayden, Randall T.
Title: Clinical correlation of influenza and respiratory syncytial virus load measured by digital PCR Document date: 2019_9_3
ID: 1sli4e5v_32
Snippet: We developed and validated two dPCR assays for quantitative detection of influenza virus (64 samples from 23 patients) and RSV (73 samples from 19 patients) in respiratory tract samples from patients with hematologic malignancies, solid tumors, and SCD. Both in patients with influenza virus and RSV infection, viral loads were associated with symptoms of infection. Furthermore, patients receiving antiviral treatment had a significantly decreased v.....
Document: We developed and validated two dPCR assays for quantitative detection of influenza virus (64 samples from 23 patients) and RSV (73 samples from 19 patients) in respiratory tract samples from patients with hematologic malignancies, solid tumors, and SCD. Both in patients with influenza virus and RSV infection, viral loads were associated with symptoms of infection. Furthermore, patients receiving antiviral treatment had a significantly decreased viral load after completion of therapy.
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