Selected article for: "ab dependent and adcc cell cytotoxicity"
Author: Schmaljohn, Alan L.; Orlandi, Chiara; Lewis, George K.
Title: Deciphering Fc-mediated Antiviral Antibody Functions in Animal Models
  • Document date: 2019_7_17
    • ID: 1755sywc_11
    Snippet: • ADCC: Ab-dependent cell mediated cytotoxicity, a collective and operational (assay-defined) term rooted in many possible, varied, and nonredundant in vitro assays that measure FeR-dependent activities facilitated by FeR-bearing cells with readouts such as: target cell lysis; phagocytosis; trogocytosis; NK cell activation; granzyme release; or ex vivo FeR binding......
    Document: • ADCC: Ab-dependent cell mediated cytotoxicity, a collective and operational (assay-defined) term rooted in many possible, varied, and nonredundant in vitro assays that measure FeR-dependent activities facilitated by FeR-bearing cells with readouts such as: target cell lysis; phagocytosis; trogocytosis; NK cell activation; granzyme release; or ex vivo FeR binding.

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