Author: Chernobrovkin, Alexey L.; Zubarev, Roman A.
Title: Detection of Viral Proteins in Human Cells Lines by Xeno-Proteomics: Elimination of the Last Valid Excuse for Not Testing Every Cellular Proteome Dataset for Viral Proteins Document date: 2014_3_11
ID: 0hrwqho8_10
Snippet: Here we describe such a balanced three-step procedure for reliable detection and relative quantification of viral proteins in proteomics data using a combination of standard approaches based on well-tested statistical models. Because of its simplicity and availability of proteomics analysis, the procedure can be easily adopted by most, if not all, cell labs. It can also be easily extended to non-viral contaminations. Moreover, proteome profiling .....
Document: Here we describe such a balanced three-step procedure for reliable detection and relative quantification of viral proteins in proteomics data using a combination of standard approaches based on well-tested statistical models. Because of its simplicity and availability of proteomics analysis, the procedure can be easily adopted by most, if not all, cell labs. It can also be easily extended to non-viral contaminations. Moreover, proteome profiling can also confirm the identity of the cell line, which is another point of recent serious concerns [26] .
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