Author: Shrestha, Ashish C.; Wijesundara, Danushka K.; Masavuli, Makutiro G.; Mekonnen, Zelalem A.; Gowans, Eric J.; Grubor-Bauk, Branka
Title: Cytolytic Perforin as an Adjuvant to Enhance the Immunogenicity of DNA Vaccines Document date: 2019_4_30
ID: 141u6ax7_16
Snippet: tic Protein rin (PRF) is a pore forming protein released by immune cells including NK cells and T lymphocytes (CTL) [91] . The 67-kilodalton PRF protein oligomerizes to form pores that channel to release granzyme into the cytosol of target cells [92] . Suicide genes inducing of target cells have been used for cancer therapies, and the role of apoptotic cell death in n, whether immune-stimulatory or immune-suppressive, is debated [93] . Recently, .....
Document: tic Protein rin (PRF) is a pore forming protein released by immune cells including NK cells and T lymphocytes (CTL) [91] . The 67-kilodalton PRF protein oligomerizes to form pores that channel to release granzyme into the cytosol of target cells [92] . Suicide genes inducing of target cells have been used for cancer therapies, and the role of apoptotic cell death in n, whether immune-stimulatory or immune-suppressive, is debated [93] . Recently, a novel hnology has been developed--termed cytolytic DNA technology-in which a truncated F is incorporated in a bicistronic DNA vector to act as a vaccine adjuvant [55] [56] [57] 94] .
Search related documents:
Co phrase search for related documents- apoptotic cell death and cytolytic dna: 1
- apoptotic cell death and cytolytic dna technology: 1
- apoptotic cell death and dna vector: 1
- apoptotic cell death and form protein: 1, 2, 3, 4
- apoptotic cell death and granzyme release: 1
- apoptotic cell death and immune cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- apoptotic cell death and immune stimulatory: 1
- apoptotic cell death and immune suppressive immune stimulatory: 1
- apoptotic cell death and NK cell: 1
- apoptotic cell death and PRF protein: 1
- apoptotic cell death role and cytolytic dna: 1
- apoptotic cell death role and cytolytic dna technology: 1
- apoptotic cell death role and dna vector: 1
- apoptotic cell death role and form protein: 1
- apoptotic cell death role and granzyme release: 1
- apoptotic cell death role and immune cell: 1
- apoptotic cell death role and immune stimulatory: 1
- apoptotic cell death role and immune suppressive immune stimulatory: 1
- apoptotic cell death role and PRF protein: 1
Co phrase search for related documents, hyperlinks ordered by date