Selected article for: "different life cycle and life cycle"
Author: Chiramel, Abhilash I.; Brady, Nathan R.; Bartenschlager, Ralf
Title: Divergent Roles of Autophagy in Virus Infection
  • Document date: 2013_1_25
    • ID: 1oawya1p_33
    Snippet: Apart from playing a major role in antiviral defense, it is becoming increasingly clear that autophagy or individual factors of the autophagy pathway can also enhance viral replication. Many viruses have evolved strategies to directly or indirectly subvert autophagy in order to promote different stages of the viral life cycle. In fact, studies involving pharmacological inhibition or gene silencing of the autophagy pathway demonstrated inhibition .....
    Document: Apart from playing a major role in antiviral defense, it is becoming increasingly clear that autophagy or individual factors of the autophagy pathway can also enhance viral replication. Many viruses have evolved strategies to directly or indirectly subvert autophagy in order to promote different stages of the viral life cycle. In fact, studies involving pharmacological inhibition or gene silencing of the autophagy pathway demonstrated inhibition of replication and spread of viruses, whereas viral induction of autophagy results in enhanced virus yields.

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