Selected article for: "dissolution profile and NTZ dissolution profile"
Author: Salas-Zúñiga, Reynaldo; Rodríguez-Ruiz, Christian; Höpfl, Herbert; Morales-Rojas, Hugo; Sánchez-Guadarrama, Obdulia; Rodríguez-Cuamatzi, Patricia; Herrera-Ruiz, Dea
Title: Dissolution Advantage of Nitazoxanide Cocrystals in the Presence of Cellulosic Polymers
  • Document date: 2019_12_25
    • ID: 034w5afv_33
    Snippet: The above-described powder dissolution experiments under non-sink conditions showed that the best improvement of the NTZ dissolution profile was achieved with the NTZ-SUC cocrystal, in the presence of Methocel ® 60 HG. To evaluate if the polymer included in the solid formulation has an effect on the dissolution kinetics of the cocrystal, four pharmaceutical powder formulations were examined with cocrystal-polymer ratios of 0.0, 1.0, 2.5 and 5.0%.....
    Document: The above-described powder dissolution experiments under non-sink conditions showed that the best improvement of the NTZ dissolution profile was achieved with the NTZ-SUC cocrystal, in the presence of Methocel ® 60 HG. To evaluate if the polymer included in the solid formulation has an effect on the dissolution kinetics of the cocrystal, four pharmaceutical powder formulations were examined with cocrystal-polymer ratios of 0.0, 1.0, 2.5 and 5.0% (w/w). The dissolution performance of the formulated solid samples was analyzed by means of powder dissolution tests using the USP 1 (basket) apparatus. A similar strategy was employed for the evaluation of formulated cocrystals of carbamazepine [29, 30] . The dissolution profiles in pH 7.5 PBS for NTZ in pure form, a 2:1

    Search related documents:
    Co phrase search for related documents
    • cocrystal polymer and dissolution profile: 1, 2, 3, 4
    • cocrystal polymer and formulated cocrystal: 1
    • cocrystal polymer and Methocel presence: 1, 2, 3
    • cocrystal polymer and NTZ dissolution: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • cocrystal polymer and NTZ dissolution profile: 1, 2, 3, 4
    • cocrystal polymer and NTZ SUC cocrystal: 1, 2, 3, 4, 5, 6, 7, 8
    • cocrystal polymer and pharmaceutical powder formulation: 1
    • dissolution performance and Methocel presence: 1, 2
    • dissolution performance and NTZ dissolution: 1, 2, 3
    • dissolution performance and NTZ dissolution profile: 1, 2
    • dissolution performance and NTZ SUC cocrystal: 1, 2
    • dissolution profile and Methocel presence: 1, 2
    • dissolution profile and NTZ dissolution: 1, 2, 3, 4, 5, 6
    • dissolution profile and NTZ dissolution profile: 1, 2, 3, 4, 5
    • dissolution profile and NTZ SUC cocrystal: 1, 2, 3, 4, 5
    • formulated cocrystal and NTZ dissolution: 1, 2
    • formulated cocrystal and NTZ SUC cocrystal: 1, 2
    • Methocel presence and NTZ dissolution: 1, 2, 3, 4, 5, 6, 7
    • Methocel presence and NTZ dissolution profile: 1, 2