Author: Kang, Hee; Park, Sung-Hyun; Yun, Jeong-Moon; Nam, Tae-Gyu; Kim, Young-Eun; Kim, Dae-Ok; Kim, Youn Jung
Title: Effect of cinnamon water extract on monocyte-to-macrophage differentiation and scavenger receptor activity Document date: 2014_3_7
ID: 0bqhbm9p_3
Snippet: Macrophages express scavenger receptors that play an important role in host defense and tissue homeostasis [9] . Macrophages not only eradicate microbes, but also clear dying cells, remove cellular debris, and eliminate metabolite buildup in the extracellular matrix. Scavenger receptors bind and internalize exogenous and endogenous damage-associated molecules such as microbial lipopolysaccharide and lipoteichoic acid, anionic phospholipids, beta .....
Document: Macrophages express scavenger receptors that play an important role in host defense and tissue homeostasis [9] . Macrophages not only eradicate microbes, but also clear dying cells, remove cellular debris, and eliminate metabolite buildup in the extracellular matrix. Scavenger receptors bind and internalize exogenous and endogenous damage-associated molecules such as microbial lipopolysaccharide and lipoteichoic acid, anionic phospholipids, beta amyloid peptide, modified low density lipoprotein (LDL), and advanced glycation end products [12] . In the atherosclerotic lesion where reactive oxygen species (ROS) and macrophage-colony stimulating factor (M-CSF) are abundant, macrophages are stimulated to upregulate scavenger receptors and take up modified LDL [13, 14] . Clearance of lipids through scavenger receptors is protective in early atherosclerotic lesions, but prolonged exposure to lipids causes cell death, leading to plaque instability and thrombus formation.
Search related documents:
Co phrase search for related documents- amyloid peptide and cell death: 1
- amyloid peptide and glycation end: 1, 2
- amyloid peptide and glycation end product: 1, 2
- atherosclerotic lesion and density lipoprotein: 1
- atherosclerotic lesion and early atherosclerotic lesion: 1
- cell death and density lipoprotein: 1, 2, 3
- cell death and die cell: 1
- cell death and extracellular matrix: 1, 2, 3, 4, 5, 6, 7, 8, 9
- cell death and glycation end: 1, 2
- damage associate and extracellular matrix: 1
- density lipoprotein and extracellular matrix: 1
- density lipoprotein and glycation end: 1
- extracellular matrix and glycation end: 1, 2, 3
Co phrase search for related documents, hyperlinks ordered by date