Author: Chiramel, Abhilash I.; Brady, Nathan R.; Bartenschlager, Ralf
Title: Divergent Roles of Autophagy in Virus Infection Document date: 2013_1_25
ID: 1oawya1p_25
Snippet: The role of autophagy in delivering viral PAMPs to TLRs and the subsequent induction of autophagy upon TLR activation indicates the existence of a positive feedback loop. This feedback loop might not only play an important role in the autophagic sequestration and delivery of PAMPs to endosomal compartments, but also serve for autolysosomal degradation of virions and viral proteins, as well as for antigen presentation via MHC-I and MHC-II molecule.....
Document: The role of autophagy in delivering viral PAMPs to TLRs and the subsequent induction of autophagy upon TLR activation indicates the existence of a positive feedback loop. This feedback loop might not only play an important role in the autophagic sequestration and delivery of PAMPs to endosomal compartments, but also serve for autolysosomal degradation of virions and viral proteins, as well as for antigen presentation via MHC-I and MHC-II molecules, thereby triggering the adaptive immune response.
Search related documents:
Co phrase search for related documents- adaptive immune response and autophagy role: 1, 2, 3
- adaptive immune response and feedback loop: 1, 2, 3, 4
- adaptive immune response and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74, 75, 76, 77, 78, 79, 80, 81, 82
- adaptive immune response and important role: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22
- adaptive immune response and positive feedback loop: 1, 2
- adaptive immune response and TLR activation: 1
- adaptive immune response and viral pamp: 1
- adaptive immune response and viral protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- adaptive immune response trigger and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- antigen presentation and autophagy role: 1, 2, 3, 4
- antigen presentation and endosomal compartment: 1, 2
- antigen presentation and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- antigen presentation and important role: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
- antigen presentation and MHC II molecule: 1
- antigen presentation and TLR activation: 1, 2
- antigen presentation and viral protein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- autophagy role and feedback loop: 1
- autophagy role and immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13
- autophagy role and important role: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
Co phrase search for related documents, hyperlinks ordered by date